Prof. Dr. Ferenc Fülöp

Research topic:
Synthesis of heterocycles via ring closure and RDA reactions

Prof. Dr. Ferenc Fülöp, Dr. Márta Palkó

2-Aminocycloalkenecarboxylic acids and their derivatives are versatile starting materials for the synthesis of alicycle-condensed heterocycles of interest from both stereochemical and pharmaceutical aspects. The beta-amino acids are not only important pharmacologically, but are also used as building blocks for preparation of modified analogues of biologically active peptides.
Our research program is directed towards:
(a) Synthesis of heterocyclic compounds across ring-closing/domino ring-closing reactions by starting from unsaturated bicyclic amino acid derivatives.
(b) Investigation of the retro-Diels Alder reactions of the synthesized heterocycles.